Identification of novel pathways for biotransformation of tetrabromobisphenol A by Phanerochaete chrysosporium, combined with mechanism analysis at proteome level.
Identifieur interne : 000481 ( Main/Exploration ); précédent : 000480; suivant : 000482Identification of novel pathways for biotransformation of tetrabromobisphenol A by Phanerochaete chrysosporium, combined with mechanism analysis at proteome level.
Auteurs : Zhanghong Chen [République populaire de Chine] ; Hua Yin [République populaire de Chine] ; Hui Peng [République populaire de Chine] ; Guining Lu [République populaire de Chine] ; Zehua Liu [République populaire de Chine] ; Zhi Dang [République populaire de Chine]Source :
- The Science of the total environment [ 1879-1026 ] ; 2019.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Polybrominated Biphenyls, Proteome, Water Pollutants, Chemical.
- metabolism : Phanerochaete.
- Biodegradation, Environmental, Biotransformation.
Abstract
The investigation of tetrabromobisphenol A (TBBPA) removal by Phanerochaete chrysosporium (P. chrysosporium) was conducted. Under optimal conditions (pH 5, inoculum size of 5% (v/v), initial glucose concentration of 5 g/L, TBBPA concentration of 5 mg/L), >97% of initial TBBPA was removed after 3 days. The TBBPA metabolites, tetrabromobisphenol A glycoside, tribromobisphenol A glycoside and monohydroxylated tetrabromobisphenol A, were identified for the first time by fungi transformation as being produced by glycosylation and oxidative hydroxylation, respectively. Proteome analysis showed that P. chrysosporium significantly upregulated cytochrome P450 monooxygenase, glutathione S-transferases, UDP-glucosyltransferase, O‑methyltransferase and other oxidoreductases for TBBPA oxidative hydroxylation, reductive debromination, glycosylation, O‑methylation and oxidative cleavage for detoxification. Data from cytotoxicity tests with human hepatocellular liver carcinoma (HepG2) confirmed that TBBPA toxicity was effectively decreased by P. chrysosporium treatment. Bioaugmentation with P. chrysosporium significantly improved the removal efficiency of TBBPA in water microcosms to 63.1% within 12 h. This study suggests that P. chrysosporium might be suitable for the removal of TBBPA from contaminated water.
DOI: 10.1016/j.scitotenv.2018.12.446
PubMed: 31096345
Affiliations:
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Zhanghong" uniqKey="Chen Z" first="Zhanghong" last="Chen">Zhanghong Chen</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, PR China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong</wicri:regionArea><wicri:noRegion>Guangdong</wicri:noRegion></affiliation></author><author><name sortKey="Yin, Hua" sort="Yin, Hua" uniqKey="Yin H" first="Hua" last="Yin">Hua Yin</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, PR China. Electronic address: huayin@scut.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong</wicri:regionArea><wicri:noRegion>Guangdong</wicri:noRegion></affiliation></author><author><name sortKey="Peng, Hui" sort="Peng, Hui" uniqKey="Peng H" first="Hui" last="Peng">Hui Peng</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Jinan University, Guangzhou 510632, Guangdong, PR China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Chemistry, Jinan University, Guangzhou 510632, Guangdong</wicri:regionArea><wicri:noRegion>Guangdong</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Guining" sort="Lu, Guining" uniqKey="Lu G" first="Guining" last="Lu">Guining Lu</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, PR China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong</wicri:regionArea><wicri:noRegion>Guangdong</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Zehua" sort="Liu, Zehua" uniqKey="Liu Z" first="Zehua" last="Liu">Zehua Liu</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, PR China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong</wicri:regionArea><wicri:noRegion>Guangdong</wicri:noRegion></affiliation></author><author><name sortKey="Dang, Zhi" sort="Dang, Zhi" uniqKey="Dang Z" first="Zhi" last="Dang">Zhi Dang</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, PR China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong</wicri:regionArea><wicri:noRegion>Guangdong</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Science of the total environment</title><idno type="eISSN">1879-1026</idno><imprint><date when="2019" type="published">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biodegradation, Environmental (MeSH)</term><term>Biotransformation (MeSH)</term><term>Phanerochaete (metabolism)</term><term>Polybrominated Biphenyls (metabolism)</term><term>Proteome (metabolism)</term><term>Water Pollutants, Chemical (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Biotransformation (MeSH)</term><term>Dépollution biologique de l'environnement (MeSH)</term><term>Phanerochaete (métabolisme)</term><term>Polluants chimiques de l'eau (métabolisme)</term><term>Polybromobiphényles (métabolisme)</term><term>Protéome (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Polybrominated Biphenyls</term><term>Proteome</term><term>Water Pollutants, Chemical</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Phanerochaete</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Phanerochaete</term><term>Polluants chimiques de l'eau</term><term>Polybromobiphényles</term><term>Protéome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biodegradation, Environmental</term><term>Biotransformation</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Biotransformation</term><term>Dépollution biologique de l'environnement</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The investigation of tetrabromobisphenol A (TBBPA) removal by Phanerochaete chrysosporium (P. chrysosporium) was conducted. Under optimal conditions (pH 5, inoculum size of 5% (v/v), initial glucose concentration of 5 g/L, TBBPA concentration of 5 mg/L), >97% of initial TBBPA was removed after 3 days. The TBBPA metabolites, tetrabromobisphenol A glycoside, tribromobisphenol A glycoside and monohydroxylated tetrabromobisphenol A, were identified for the first time by fungi transformation as being produced by glycosylation and oxidative hydroxylation, respectively. Proteome analysis showed that P. chrysosporium significantly upregulated cytochrome P450 monooxygenase, glutathione S-transferases, UDP-glucosyltransferase, O‑methyltransferase and other oxidoreductases for TBBPA oxidative hydroxylation, reductive debromination, glycosylation, O‑methylation and oxidative cleavage for detoxification. Data from cytotoxicity tests with human hepatocellular liver carcinoma (HepG2) confirmed that TBBPA toxicity was effectively decreased by P. chrysosporium treatment. Bioaugmentation with P. chrysosporium significantly improved the removal efficiency of TBBPA in water microcosms to 63.1% within 12 h. This study suggests that P. chrysosporium might be suitable for the removal of TBBPA from contaminated water.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">31096345</PMID><DateCompleted><Year>2019</Year><Month>06</Month><Day>14</Day></DateCompleted><DateRevised><Year>2019</Year><Month>06</Month><Day>14</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1879-1026</ISSN><JournalIssue CitedMedium="Internet"><Volume>659</Volume><PubDate><Year>2019</Year><Month>Apr</Month><Day>01</Day></PubDate></JournalIssue><Title>The Science of the total environment</Title><ISOAbbreviation>Sci Total Environ</ISOAbbreviation></Journal><ArticleTitle>Identification of novel pathways for biotransformation of tetrabromobisphenol A by Phanerochaete chrysosporium, combined with mechanism analysis at proteome level.</ArticleTitle><Pagination><MedlinePgn>1352-1361</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0048-9697(18)35342-7</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.scitotenv.2018.12.446</ELocationID><Abstract><AbstractText>The investigation of tetrabromobisphenol A (TBBPA) removal by Phanerochaete chrysosporium (P. chrysosporium) was conducted. Under optimal conditions (pH 5, inoculum size of 5% (v/v), initial glucose concentration of 5 g/L, TBBPA concentration of 5 mg/L), >97% of initial TBBPA was removed after 3 days. The TBBPA metabolites, tetrabromobisphenol A glycoside, tribromobisphenol A glycoside and monohydroxylated tetrabromobisphenol A, were identified for the first time by fungi transformation as being produced by glycosylation and oxidative hydroxylation, respectively. Proteome analysis showed that P. chrysosporium significantly upregulated cytochrome P450 monooxygenase, glutathione S-transferases, UDP-glucosyltransferase, O‑methyltransferase and other oxidoreductases for TBBPA oxidative hydroxylation, reductive debromination, glycosylation, O‑methylation and oxidative cleavage for detoxification. Data from cytotoxicity tests with human hepatocellular liver carcinoma (HepG2) confirmed that TBBPA toxicity was effectively decreased by P. chrysosporium treatment. Bioaugmentation with P. chrysosporium significantly improved the removal efficiency of TBBPA in water microcosms to 63.1% within 12 h. This study suggests that P. chrysosporium might be suitable for the removal of TBBPA from contaminated water.</AbstractText><CopyrightInformation>Copyright © 2019 Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Zhanghong</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, PR China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yin</LastName><ForeName>Hua</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, PR China. Electronic address: huayin@scut.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peng</LastName><ForeName>Hui</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Chemistry, Jinan University, Guangzhou 510632, Guangdong, PR China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lu</LastName><ForeName>Guining</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, PR China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Zehua</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, PR China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dang</LastName><ForeName>Zhi</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Key Laboratory of Ministry of Education on Pollution Control and Ecosystem Restoration in Industry Clusters, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou 510006, Guangdong, PR China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2019</Year><Month>01</Month><Day>02</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Sci Total Environ</MedlineTA><NlmUniqueID>0330500</NlmUniqueID><ISSNLinking>0048-9697</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011075">Polybrominated Biphenyls</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D020543">Proteome</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014874">Water Pollutants, Chemical</NameOfSubstance></Chemical><Chemical><RegistryNumber>FQI02RFC3A</RegistryNumber><NameOfSubstance UI="C020806">tetrabromobisphenol A</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D001673" MajorTopicYN="N">Biodegradation, Environmental</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001711" MajorTopicYN="Y">Biotransformation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020075" MajorTopicYN="N">Phanerochaete</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011075" MajorTopicYN="N">Polybrominated Biphenyls</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020543" MajorTopicYN="N">Proteome</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014874" MajorTopicYN="N">Water Pollutants, Chemical</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Phanerochaete chrysosporium</Keyword><Keyword MajorTopicYN="N">Proteomics</Keyword><Keyword MajorTopicYN="N">TBBPA glycoside</Keyword><Keyword MajorTopicYN="N">Tetrabromobisphenol A</Keyword><Keyword MajorTopicYN="N">Tri-BBPA glycoside</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year><Month>11</Month><Day>05</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2018</Year><Month>12</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>12</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>5</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>5</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>6</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">31096345</ArticleId><ArticleId IdType="pii">S0048-9697(18)35342-7</ArticleId><ArticleId IdType="doi">10.1016/j.scitotenv.2018.12.446</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Chen, Zhanghong" sort="Chen, Zhanghong" uniqKey="Chen Z" first="Zhanghong" last="Chen">Zhanghong Chen</name></noRegion><name sortKey="Dang, Zhi" sort="Dang, Zhi" uniqKey="Dang Z" first="Zhi" last="Dang">Zhi Dang</name><name sortKey="Liu, Zehua" sort="Liu, Zehua" uniqKey="Liu Z" first="Zehua" last="Liu">Zehua Liu</name><name sortKey="Lu, Guining" sort="Lu, Guining" uniqKey="Lu G" first="Guining" last="Lu">Guining Lu</name><name sortKey="Peng, Hui" sort="Peng, Hui" uniqKey="Peng H" first="Hui" last="Peng">Hui Peng</name><name sortKey="Yin, Hua" sort="Yin, Hua" uniqKey="Yin H" first="Hua" last="Yin">Hua Yin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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